Symbol
Name
ID

Hspg2
perlecan (heparan sulfate proteoglycan 2)
MGI:96257

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes	Single umbilical artery	Abnormal heart morphology	Pulmonary arterial hypertension	Arrhythmia
Disease(s) Associated with HSPG2	Single umbilical artery	Abnormal heart morphology	Pulmonary arterial hypertension	Arrhythmia
Schwartz-Jampel syndrome 1
Silverman-Handmaker type dyssegmental dysplasia

Mouse Phenotypes

abnormal ascending aorta and coronary artery attachment

dilated liver sinusoidal space

abnormal cardinal vein morphology

abnormal myocardium layer morphology

abnormal myocardium compact layer morphology

abnormal cardiac outflow tract development

absent conotruncal ridges

conotruncal ridge hyperplasia

abnormal conotruncus septation

abnormal heart and great artery attachment

transposition of great arteries

abnormal semilunar valve morphology

abnormal aortic valve morphology

abnormal pulmonary valve morphology

hemopericardium

abnormal pericardium morphology

aneurysm

lung hemorrhage

hemorrhage

intracranial hemorrhage

skin hemorrhage

irregular heartbeat

Availability

Mouse Genotype

Hspg2^tm1Ref/Hspg2^tm1Ref

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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